International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


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Doctoral Thesis | Dentistry | India | Volume 12 Issue 12, December 2023


Evaluation of Pain by Using Intravenous Paracetamol as Pre-Emptive Drug in Mandibular 3rd Molar Surgery - An Experimental Study

Dr Samruddhi Danave | Dr Rahul Laturiya | Dr Sheeraz Badal | Dr Minal Sonare | Dr Punam Nagargoje | Dr Varsha Jaju


Abstract: This experimental study aimed to compare and evaluate the efficacy of pre-surgical single dose with post-surgical single dose of intravenous Paracetamol in reducing pain, frequency, and dosages of rescue analgesics in patients undergoing mandibular third molar surgery. The study involved 60 patients, and the efficacy of pre-surgical dose of intravenous Paracetamol in reducing post-operative pain was assessed. The findings suggest that pre-surgical dose of intravenous Paracetamol significantly reduces pain after mandibular third molar surgery. Aim: To compare and evaluate the efficacy of pre-surgical single dose with post-surgical single dose of intravenous Paracetamol in reducing pain, frequency, and dosages of rescue analgesics. Objectives: 1) To evaluate efficacy of pre-surgical dose of intravenous Paracetamol for reduction of pain during mandibular third molar surgery. 2) To evaluate whether intravenous Paracetamol has potent analgesic effect during &/or after mandibular third molar surgery. Methods: An experimental study carried out indepartment of Oral and Maxillofacial Surgery. Total60 patients were selected based on inclusion and exclusion criteria. Informed consent was obtained fromall the patients involved in the study. Patients who will fulfil the study criteria were divided into three equal groups based on preoperative and postoperative dose of Paracetamol and placebo. Conclusion: From our study, we would like to conclude that pre-surgical dose of intravenous Paracetamol significantly reduces pain after mandibular third molar surgery.


Keywords: Pain, Mandibular Third molar, Paracetamol, Pre-emptive drug


Edition: Volume 12 Issue 12, December 2023,


Pages: 282 - 288


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