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Masters Thesis | Biological Sciences | India | Volume 12 Issue 7, July 2023
Urinary Iodine in Second Trimester Pregnancy: A Cross Sectional Study in District of Pulwama
Asif Ahmad [2] | Arisha Noor | Shah Yasir Yousuf
Abstract: Iodine is important trace element and its deficiency is a common health problem affecting a huge population, particularly pregnant women and children. The physiological role of iodine in the human body is synthesis of thyroid hormones. Thyroxine is approximately 60% iodine by weight. If iodine intake falls below approximately 100?g/day, Thyroid Stimulating Hormone (TSH) secretion is augmented, which increases plasma inorganic iodide clearance. To correlate urinary iodine with serum TSH in the second trimester of pregnant women. 168 subjects were included in the study from tertiary care hospital. A random urine sample was collected. Iodine was estimated by ammonium persulfate method and TSH values were collected from the OBG department of the subjects enrolled. Pearson correlation coefficient was done. Median UI 136.67 (256.80-360.76) ?g/L, median TSH 1.68(0.15-9.48) mIU/L. There was no significant correlation between UI and serum TSH with r = (0.076, (p = 0.368). Conclusion: Urinary iodine is a marker for population iodine status. A preferable biomarker is necessary to know the iodine status of individual which include not only nutritional biomarker and also required to organise reference range for TSH.
Keywords: Urinary Iodine, Pregnancy, ammonium persulfate, TSH
Edition: Volume 12 Issue 7, July 2023,
Pages: 345 - 348