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Research Paper | Anaesthesiology | India | Volume 12 Issue 6, June 2023 | Popularity: 5.1 / 10
Comparison of the Effectiveness of Hyperbaric Levobupivacaine (0.5%) and Hyperbaric Bupivacaine (0.5%) Combined with Fentanyl in Patients Undergoing Caserean Section
Dr. Bhumika Chaudhari, Dr. Neepa S Patel
Abstract: Introduction: The most popular local anaesthetic for spinal anaesthesia in patients having an elective caesarean delivery is hyperbaric bupivacaine. Enantiomers could possess the same desired properties but fewer adverse effects. In comparison to bupivacaine, levobupivacaine, the S (-)-enantiomer of bupivacaine, has recently been approved for obstetric spinal and epidural anesthesia. Hence, the study has been formulated to sensory and motor effect with hyperbaric levobupivacaine and bupivacaine with fentanyl in patients undergoing caserean section. Aim & Objective: To compare analgesic and anesthetic effectiveness of hyperbaric 0.5% levobupivacaine and hyperbaric 0.5% bupivacaine in combination with fentanyl in spinal anesthesia in patients undergoing caserean section. Method: Patients with ASA Status I & II were divided into two groups of 27 patients each at randomly. Group LF: 27 patients receiving 0.5% hyperbaric levobupivacaine 2 ml (10 mg) combined with 25 ?g fentanyl. Group BF: 27 patients receiving 5 ml (10 mg) Bupivacaine combined with 25 ?g fentanyl. During surgery, sensory and motor levels, and hemodynamic monitoring were noted. Postoperatively, the total time of the motor and sensory block and the period of rescue analgesia were noted. Result: Group BF had faster sensory onset time at T10. Group LF had longer sensory block and analgesia, and two segment regression time was also longer in Group LF. Hemodynamic parameters were comparable between two groups. Conclusion: The combination of intravenous levobupivacaine and fentanyl increased the duration of the sensory block and the relief from pain without extending the motor block, which may have aided in the onset of early ambulation.
Keywords: hyperbaric levobupivacaine, caserean section, Spinal anaesthesia
Edition: Volume 12 Issue 6, June 2023
Pages: 1608 - 1612
DOI: https://www.doi.org/10.21275/SR23615022825
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