International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


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Review Papers | Physiotherapy | India | Volume 12 Issue 6, June 2023


Prevalence of Stroke in Post COVID-19 Patients and their Association with Comorbidities: Literature Review

G. Naga Teja Sri | Prasanna Mohan [3]


Abstract: Introduction: In early December 2019, several cases of unknown origin pneumonia were described in Wuhan, the capital of Hubei Province in China. In less than a 4month interval, a novel coronavirus, SARS-CoV-2 (COVID-19), was identified as the causative agent, and the infection quickly spread from China to the rest of the world, becoming a pandemic by March 2020. Brain is the potential target to COVID-19, just as the lungs, due to expression of angiotensin-converting enzyme (ACE 2) receptors on the glial cells and neurons of the central nervous system. There have been reports on stroke surge, especially among elderly patients, suffering from COVID-19. Many of the patients presenting with stroke might already have underlying cerebrovascular risk factors, such as hypertension, hyperlipidemia, diabetes mellitus, smoking, or previous history of stroke. The occurrence of cerebrovascular events in critically ill patients with underlying medical co-morbidities is therefore potentially related to the direct effect of the infection Itself or inappropriate host response. Recent research from across the globe indicates that SARS-CoV-2 infection is connected with both ischemic and hemorrhagic strokes. Stroke has emerged as a severe neurological complication of SARS-CoV-2 infection. The need of the study: There are many studies regarding neurological disorders after recovery from COVID-19. This study mainly focuses on COVID-19 related strokes and whether these strokes are causing because of the presence of comorbidities. And their interrelation with each other. It is important to know their relation because of increasing number of COVID related strokes. Objectives: To Review the articles which have studied about COVID-19 related strokes and their association with comorbidities. Sources of data: Relevant studies from onset of COVID-19 i. e. from 2019 - 2022 were obtained from the following data bases: PUBMED, SCIENCE DIRECT, GOOGLE SCHOLAR library using key words COVID-19, corona virus pandemic, Neurological disorders, prevalence of stroke. Conclusion: Cerebrovascular events are relatively common findings in COVID-19 infection, and they could have a multifactorial etiology. COVID-19 Related strokes are more common between the age group 40 - 70. Males are affected more when compared to females. Symptoms like headache, loss of sensation, weakness in extremities, poor cognitive abilities are seen in patients after recovery from COVID-19. Cerebrovascular symptoms began at a median of 10 days (range 0-33) after onset of respiratory illness.


Keywords: COVID-19


Edition: Volume 12 Issue 6, June 2023,


Pages: 1188 - 1193


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