International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


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Case Studies | Paediatrics | Nigeria | Volume 12 Issue 6, June 2023


Premature Adrenarche in a 4 year Old Nigerian Girl: A Case Report with Review of Literature

Abdallah R. J | Abah R. O | Ochoga M. O | Aliu-Isah O. O.


Abstract: Premature adrenarche refers to an early increase in adrenal androgen production that usually results in the development of pubic hair or pubarche before the age of 8 years in girls and 9 years in boys with or without axillary hair and pubertal odour, and with no other signs of sexual development. We report a case of 4 year old girl who presented with complaint of increasing pubic hair noticed from birth with subsequent development of axillary hair and body odour from 2 years of age. Physical examination revealed a body mass index of 16.3kg/m2 and pubic hair at Tanner stage 2. The biochemical results were within the reference limits for age and sex except for low FSH and LH. Based on the clinical and biochemical features a diagnosis of premature adrenarche was made. The parents were counseled and the child is currently on follow - up in the clinic. Premature adrenarche though a benign condition, in girls with LBW, requires follow - up due to higher risk of obesity - related metabolic disturbance.


Keywords: Premature adrenarche, four year old girl, Paediatrics, Case report, Nigeria


Edition: Volume 12 Issue 6, June 2023,


Pages: 384 - 386


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