Vogt-Koyanagi-Harada Syndrome following Anti-SARS-COV2 Vaccine

Dr. Hrutuja Kantrao Dhumale | Dr. Satish S. Desai | Dr. Swapnali Bandgar

Abstract: Vogt-Koyanagi-Harada syndrome is a multisystem disorder with chronic, bilateral, non-necrotizing, diffuse granulomatous panuveitis and exudative retinal detachment associated with neurological, audiovestibular, dermatological abnormalities. Aim and objective: 1) to determine Possibility of anti-SARS-COV 2 vaccination associated with triggering VKH syndrome. 2) Role of early diagnosis and treatment. We are reporting on patient treated Early and in sustained fashion who was asymptomatic and developed symptoms after anti-SARS-COV 2 vaccination. Conclusion: Vogt-Koyanagi-Harada syndrome results from an autoimmune inflammatory process which can be controlled with early diagnosis and treatment. Immunological mechanisms and dysregulation of the immune system may play a significant role in association between VKH syndrome and vaccination. Although it is difficult to determine causality, this report enlighten possible association between VKH and vaccination.

Keywords: VKH, Vogt-Koyanagi-Harada, IL - Interleukin, HLA - Human Leukocyte antigen, OCT - Optical Coherence Tomography, OD - Oculus Dexter, OS - Oculus Sinister

Edition: Volume 12 Issue 5, May 2023,

Pages: 205 - 210