Management of Membranous Glomerulonephritis in Pregnancy: A Multidisciplinary Approach

Preeti Lewis, Annapurna Brahma

Abstract: We present a case of 21-year-old female, gravid 2, para 1 and intra-uterine fetal demise 1, a biopsy proven case of membranous glomerulonephritis, who had a past obstetrical history complicated by uncontrolled blood pressure, early onset preeclampsia, and a fetal demise at 30 weeks, COVID 19 positive status requiring Ventilatory Support .Her blood pressure normalized after previous pregnancy. In the recent pregnancy, she remained normotensive and initially presented with normal blood urea nitrogen and creatinine levels. However, after the early first trimester, she developed nephrotic range proteinuria, hypoalbuminemia, and peripheral edema which was diagnosed early and managed appropriately .Afterwards, all clinical symptoms resolved and laboratory values normalized and patient delivered vaginally. We review the clinical course, diagnosis, and management of known case of membranous glomerulonephritis in pregnancy.

Keywords: Membranous glomerulonephritis, proteinuria, preeclampsia