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Review Papers | Pharmaceutical Science | India | Volume 12 Issue 4, April 2023
Pharmacovigilance in the Age of Precision Medicine: Opportunities and Challenges
Abstract: Precision medicine, also known as personalized medicine, is a rapidly advancing field that aims to optimize treatment outcomes by tailoring medical interventions to individual patients based on their genetic, environmental, and lifestyle characteristics. While precision medicine holds great promise in revolutionizing healthcare, it also presents unique challenges in terms of safety monitoring and adverse event reporting. Pharmacovigilance, which includes scientific research and various activities associated with identifying, evaluating, comprehending, and preventing adverse effects or other drug - related issues, plays a crucial part in protecting the safety of precision medicine interventions. This article aims to provide an overview of the current landscape of pharmacovigilance in the era of precision medicine, including its general function, opportunitiesit presents, such as the potential for enhanced safety and efficacy through personalized therapies, improved understanding of rare adverse events, and the use of real - world data for safety monitoring. It also discusses the challenges that precision medicine poses for pharmacovigilance, including the need for novel approaches to signal detection, the complexity of managing adverse events in patient populations, and ethical considerations surrounding the use of genetic and molecular data. The paper concludes with recommendations for optimizing pharmacovigilance strategies in the era of precision medicine, including the importance of interdisciplinary collaboration, the need for robust data management and analysis, and the imperative of ensuring patient privacy and consent. Overall, pharmacovigilance remains an indispensable component of precision medicine, and careful consideration of its opportunities and challenges is crucial for ensuring the safe and effective use of personalized therapies in clinical practice.
Keywords: Precision medicine, personalized medicine, pharmacovigilance, adverse event reporting, real - world data, molecular data
Edition: Volume 12 Issue 4, April 2023,
Pages: 1344 - 1348