Development of Test Method for Assessment of In-Vitro Degradation of Medical Devices

Minocha Dr. Pramod Kumar, Kothwala Dr. Deveshkumar Mahendralal, Shaikh Amirhamzah Mahmadiqbal, Patel Chirag P

Abstract: The objective of this study is to present test results that have been reported from an in-vitro, real-time degradation study of a circular knitted mesh of a biodegradable medical device. The knitted mesh on the stent eroded up until that point in the trial, which lasted for 6-7 months at 37??1?C. Hence, in this study, the degradation of a circular knitted mesh formed of 28 micron monofilament Poly D, L-lactide-co-glycolic acid (PLGA) 8523 of biodegradable medical device was evaluated under in-vitro, real-time degradation conditions.

Keywords: Knitted mesh, biodegradable, in-vitro degradation, real time