International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


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Study Papers | Obstetrics and Gynecology | India | Volume 12 Issue 3, March 2023


Prospective Study of Ultrasonography and CA-125 with Post Operative HPE Report in Management of Ovarian Cyst in Tertiary Care Hospital

Dr. Shaik Baby Haseena | Dr. Ramavathu Sravani | Dr. Y. Annapoorna


Abstract: Background: Ovarian masses are one of the most frequently identified entities in gynaecological practice. Ultrasonography and serum Cancer antigen 125 [Ca-125] levels usually provide sufficient information for a presumptive diagnosis. Post operative HPE report helps in differentiating the ovarian cyst from benign to malignant. Objective: To determine whether serum Ca-125 levels in addition to tumour size and ultrasonography findings and post operative HPE report can help in differentiating benign ovarian cyst from malignant. Methods: A prospective study was conducted in 53 cases diagnosed with ovarian cyst from 1st January 2022 to 1st January 2023 in department of Obstetrics and gynaecology, in a tertiary care hospital. The patients clinical history, Ca-125, ultrasonographic findings and the HPE reports were studied. Results: During the study period, a total of 53 women were surveyed, the mean age group is around 36.4 years, among all the study subjects 13.2% were malignant of which 7.6% women were diagnosed as serous cystadenocarcinoma.7.54% of malignant cases in the study had fallen under ORADS-4, serum CA-125 value is <35U/ml in 7.54% malignant cases. Conclusion: As a standalone modality, serum CA-125 value >35U/ml in predicting ovarian cancer revealed modest diagnostic accuracy, hence there is a need for careful evaluation of serum CA-125 value in the reproductive age group and that of early stage ovarian malignancy whereas ORADS Scoring system is supportive in pre operative evaluation of benign versus malignant ovarian tumours.


Keywords: Ovarian cyst, Ca-125, Histopathological examination report


Edition: Volume 12 Issue 3, March 2023,


Pages: 366 - 369


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