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Research Paper | Ophthalmology | India | Volume 12 Issue 3, March 2023

Effect of Myopia and Axial Length on Peripapillary Retinal Nerve Fiber Layer Thickness Using Spectral Domain Optical Coherent Tomography

Dr. Kalpana Deshmukh | Dr. Netaji Garad | Dr. Narayan Arvikar | Dr. Ashwini Patil

Abstract: Background: Myopia is a refraction error in which parallel rays of light coming from infinity are focused in front of retina with a accommodation at rest. It results in many pathological changes like thinning of RNFL. RNFL thickness measurement is sensitive for detection of glaucoma and it correlates with severity of functional deficit in the visual field. RNFL thickness can be measured with OCT which is high resolution cross-sectional imaging technology used for retinal imaging. Aim: To evaluate the effect of myopia and axial length on peripapillary RNFL thickness using spectral domains OCT Material & Methods: Randomly selected 100 myopic patients between age 15-40yrs excluding patients with history of any type of glaucoma, severe ocular trauma ,refractive surgery, strabismus, retinal diseases, uveitis, refractive errors other than myopia, amblyopia, corneal abnormalities, media opacities, ocular hypertension, any neurological diseases that could affect optic nerve head underwent detailed ocular examination including visual acuity, refraction, IOP measurements, visual field testing, fundus examination, axial length measurement, RNFL thickness measurement using SD-OCT. Results: A significant, strong association found between axial length and RNFL thickness. RNFL thickness decreases as axial length increases in all four quadrants. Average 360 degree RNFL thickness (mean?SD) in all 200 eyes was 92.30?10?m. The ?p? value was <0.0001, which was significant. Conclusion: It was found from our results that RNFL thickness decreases with increase in axial length and increase in myopic refractive error. Thus axial length affected the average RNFL thickness and myopia affected the RNFL thickness distribution. Prevalence of glaucoma is higher in myopic eyes thus myopia may be a confounded in addition to being a risk factor

Keywords: Myopia, axial length, glaucoma, RNFL thickness, SD-OCT

Edition: Volume 12 Issue 3, March 2023,

Pages: 238 - 241