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Research Paper | Medical Science | India | Volume 12 Issue 2, February 2023

Evaluation of Safety and Performance of Bioresorbable Occluder Implant in Treating Atrial Septal Defect

Dr. Pramod Kumar Minocha | Dr. Deveshkumar Mahendralal Kothwala | Zahidbeg A Mirza | Tejas P. Thakor

Abstract: A large, long - term atrial septal defect (ASD) or imperfection can harm the heart and lungs. Medical procedure like heart surgery is fundamental procedure to fix an atrial septal defect by medical device and to prevent complications. The goal of the current study is to evaluate the efficacy and safety of a bioresorbable occluder that was developed in - house for patients with ASD disease. This study depicts information based on animal study in porcine heart model for the developed bioresorbable ASD occluder, as well as the safety of the device in the designated area after the implantation. For assurance of present research, animal study has been performed to occlude an atrial septal wall utilizing a standard technique and successfully implanted a bioresorbable ASD occluder device in the defect size of 0.9 cm affirmed by angiography and Transthoracic Echocardiogram (TTE), After 180 days of animal study, it is claimed that the, present research work could be recommended for a preclinical study to treat atrial septal defect in humans.

Keywords: Arial Septal Defect (ASD), Bioresorbable Occluder (BRO), porcine heart model

Edition: Volume 12 Issue 2, February 2023,

Pages: 1510 - 1514