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Research Paper | Orthopedic | India | Volume 12 Issue 2, February 2023

Prospective Study to Assess the Osteogenic Potential of Cissus Quadrangularis in Tibia Fractures Treated with Intramedullary Interlocking Nailing

Dr. Vaibhav Chaurasia | Dr. Karthik SR | Dr. Sathik Babu M B

Abstract: A routine fracture of tibia matures in about 16 to 20 weeks and hence hinders normal function significantly. To speed up the healing process and enable early function, alternatives are being investigated. The objective of this prospective study was to evaluate the osteogenic potential of the medication Cissus quadrangularis (CQ) on the healing of tibial fractures. Design Randomized prospective trial. Results: Alkaline phosphatase levels in the CQ group increased statistically significantly compared to the control group, according to the analysis between the groups. Clinical findings (reduction in pain and mobilisation) and other biochemical findings (serum calcium, serum phosphorous) did not statistically differ between the CQ and control groups. However, radiographic findings (callus formation) were found to be marginally better in the CQ group as compared to the control group. Conclusion: We concluded that a larger sample size is necessary to determine the absolute value of CQ before incorporating it into the fracture regimen because there was not a statistically significant improvement in practically all measures, with the exception of the alkaline phosphatase levels.

Keywords: Tibia fracture, IMIL nailing, Ciss quadrangularis

Edition: Volume 12 Issue 2, February 2023,

Pages: 1226 - 1229