Early Diagnostic Tools of Macrophage Activation Syndrome in Children with Systemic Juvenile Idiopathic Arthritis

Gargi R. Nair, Anupama .D, Harshamoorthi .C .S

Abstract: Macrophage activation syndrome (MAS) is a rare complication of childhood with rheumatic disease. It is potentially acute disorder. MAS is one of the leading cause of morbidity and mortality in patients with SJIA. It is characterized by persistent high fever, pancytopenia, purpura, encephalopathy, DIC.

Keywords: macrophage activation syndrome, haemophagocytic lymphohistocytosis, systemic juvenile idiopathic arthritis, hyperferritinemia