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Analysis Study Research Paper | Medicine | India | Volume 12 Issue 2, February 2023
Chronic Kidney Disease Pre and Post Hemodylasis
Abstract: Introduction: Chronic kidney disease is defined as kidney damage or GFR less than 60 ml / min / 1.73m2 for at least three months. Aim: To assess the effect of hemodialysis on urea creatinine and calcium levels in patients diagnosed with chronic kidney disease. Methodology: Serum urea was estimated by enzymatic method, serum creatinine by jaffes method and serum calcium by phosphotungstic method on biochemistry semiautoanalyser. Material & Method: Ptient between age group 30-60 yrs of both genders attending nephrology opd with chronic kidney disease undergoing Hemodialysis and willing to participate in study were enrolled in this study. Results: Study shows serum creatinine levels in pre and post HD group. Pre-HD had mean values of creatinine levels 10.9+-2.5 which are higher than the normal range {up to 1.4 mg/dl} and post HD had mean value of 6.0 +- 1.8. The results showed that the process of dialysis leads to a significant fall in mean serum creatinine levels {p < 0.001) but the values of creatinine are still higher than the normal range. Conclusion: The effectiveness of dialysis in reversing any complication of uremia depends on the nature of that complication. Those disturbances which are due to the accumulation of a uremia toxin may be reversible if that toxin is dialyzable and the removal rate by dialysis outstrips its generation rate.
Keywords: hemodialysis, serum creatinine, serum calcium, serum urea, chronic kidney disease
Edition: Volume 12 Issue 2, February 2023,
Pages: 356 - 358