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Case Studies | Pathology | India | Volume 12 Issue 1, January 2023

Spindle Cell Carcinoma - A Rare Variant of Metaplastic Carcinoma of Breast; A Case Report with Review of Literature

Nanda Patil ^[12] | Suresh Bhosale | Devika Borade ^[3]

Abstract: Metaplastic carcinoma comprises of a rare and heterogenous group of breast cancers characterised by differentiation of neoplastic epithelium into squamous cells and/or mesenchymal looking elements. Spindle cell carcinoma is a rare variant of metaplastic carcinoma which shows predominantly spindle cells. It has a poor prognosis with a high rate of local recurrence and distant metastasis. We present a rare case of spindle cell carcinoma of the breast in a 65 year old female patient to highlight its rare occurrence and challenging diagnosis as well as poor outcome.

Keywords: Breast cancer, Immunohistochemistry, Metaplastic carcinoma, Spindle cell carcinoma

Edition: Volume 12 Issue 1, January 2023,

Pages: 1039 - 1042