Evaluating Cytokines and Antimicrobial Peptides as Diagnostic Biomarkers in Colorectal Cancer and Adenomatous Polyps

Bayramova Narmin, Hasanova Shayman

Abstract: This study investigates the role of interleukin 6 IL - 6, tumor necrosis factor TNF - , and fatty acid binding protein FABP as diagnostic biomarkers in patients with colorectal cancer and adenomatous polyps. Analyzing blood serum samples from 80 colorectal cancer patients, 17 adenomatous polyp patients, and 25 healthy individuals, the study explores the diagnostic potential of these biomarkers. The findings indicate significant differences in the levels of these biomarkers among the groups, underscoring their potential in differential diagnosis. Considerable reduction of content of FABP in patients with malignant tumors of bowels on the relative control is also revealed. In patients with adenomatous polyposis, a significant increase in FABP was observed than with bowel tumors. Thus, all these markers can be used for early diagnosis and screening for bowel cancer.

Keywords: IL - 6 interleukin 6, TNF - tumor necrosis factor, FABP fatty acid binding protein

How to Cite?: Bayramova Narmin, Hasanova Shayman, "Evaluating Cytokines and Antimicrobial Peptides as Diagnostic Biomarkers in Colorectal Cancer and Adenomatous Polyps", Volume 12 Issue 12, December 2023, International Journal of Science and Research (IJSR), Pages: 1917-1920, https://www.ijsr.net/getabstract.php?paperid=SR231221204200, DOI: https://dx.doi.org/10.21275/SR231221204200