Lateral Flow Assay: A Point of Care Solution

Edwina Jospiene M, Dr. G. Vijaiyan Siva, Dr. S. Subramaniam, Dr. Shyama Subramaniam

Abstract: Lateral flow assays (LFA) are the technology behind economical, easy, quick and transportable detection devices popular in biomedicine, agriculture, food and environmental sciences. This review presents an overview of the principle of the method and the critical components of the assay, focusing on lateral flow immunoassays. This type of assay has recently attracted considerable interest because of its potential to provide instantaneous diagnosis directly to patients, especially during pandemic. The range and interpretation of results and parameters used for the evaluation of the assay will also be discussed. The main advantages and disadvantages of LFAs will be summarized and relevant future improvements to testing devices and strategies will be proposed. Finally, the major recent advances and future diagnostic applications in the LFA field will be explored.

Keywords: Nitrocellulose membrane, point - of - care, Rapid detection kit, capillary flow assay, Immuno chromatography assay, Nanotechnology, Multiplexing

How to Cite?: Edwina Jospiene M, Dr. G. Vijaiyan Siva, Dr. S. Subramaniam, Dr. Shyama Subramaniam, "Lateral Flow Assay: A Point of Care Solution", Volume 12 Issue 12, December 2023, International Journal of Science and Research (IJSR), Pages: 1218-1224, https://www.ijsr.net/getabstract.php?paperid=SR231215113045, DOI: https://dx.doi.org/10.21275/SR231215113045