Levetiracetamas a Brain Tumor Post Operation Seizure Prevention Drug

Dr. Malvin Giovanni | Dr. Dr. I Putu Pramana Suarjaya | Dr. I. B. Krisna Jaya Sutawan

Abstract: Levetiracetam is a new generation antiepileptic drug that has a small side effect and interaction that is lesser than Fenitoin. The use of this drug covers as prevention for post operation seizure for patients who are at high risk to experience such seizure. This case reports a male, 25 years; with IntraaxialRegio Frontal Sinistratumor with suspect Low grade Glioma and Symptomatic Epilepsy undergoes an Awake Craniotomy to remove the tumor. The patient had experienced 5 episodes of seizures although his condition has been controlled with Fenitoin and Carbamazepine as antiepileptic drug. This case reports 3 repeated seizures occurredwithin16 hours post operation and therefore the antiepileptic drug of Levetiracetam was introduced. After the new drug was administered, seizure was reported absent until the patient was discharged. Seizure post brain tumor surgery is a serious complication, usually caused by the activity of surgery or an emergency medical condition that requires immediate therapy and care. This occurrence is related to the remaining neurological symptoms which may increase the patient?s morbidity and decrease the quality of life. Giving the right antiepilepsy drug before and after surgery is expected to increase chances of post-operative seizure for patients who are at high risk, therefore reducing hospitalization duration and reducing cost of hospitalization.

Keywords: Epilepsy, Fenitoin, Post Operation seizure, Levetiracetam, brain tumor

Edition: Volume 12 Issue 12, December 2023,

Pages: 898 - 903