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Review Papers | Dentistry | India | Volume 12 Issue 1, January 2023

Periodontal Inflamed Surface Area (PISA): A Measuring Factor for Local Periodontal Inflamed Burden Connecting to Systemic Inflammation: A Comprehensive Review

Dr Kirti S Vachhani | Dr Neeta V Bhavsar

Abstract: Periodontitis is a type of systemic immune inflammation that is caused by the complex infection of a variety of microorganisms in the subgingival plaque and the imbalance of the microbial ecological environment in the mouth. It is a chronic inflammatory disease resulting in tissue destruction and periodontal pockets formation in periodontitis-affected tissues. An ulcer surface is formed on the inner surface of the periodontal pocket by disrupting the continuity of epithelial cells, which results in easy bleeding. This indicates that a mild chronic inflammatory condition persists throughout the body, not just in the periodontal tissue. Approximately 10% of the world?s population has severe periodontitis (Frencken et al., 2017).

Keywords: Chronic Periodontitis, PISA, Local and Systemic Inflammation Chronic Periodontitis, PISA, Local and Systemic Inflammation

Edition: Volume 12 Issue 1, January 2023,

Pages: 624 - 629