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Review Papers | Microbiology | India | Volume 12 Issue 12, December 2023
Evaluation of Polyherbal Gel Formulations and Investigation of their Efficacy against Microorganisms Causing Skin Diseases
Rachna Sahu | Dr. Ritu Thakur Bais | Dr. Sunil Kumar Snehi [2]
Abstract: Skin diseases, caused by various microorganisms, are a global health concern, often necessitating novel and effective treatment strategies. Polyherbal gel formulations, which harness the therapeutic potential of multiple natural ingredients, have emerged as promising candidates for addressing skin maladies. This review paper compiles and critically analyzes existing research to evaluate the efficacy of polyherbal gel formulations against microorganisms causing skin diseases. The paper begins by exploring the diverse herbal ingredients commonly used in these formulations and delves into their traditional and modern applications in dermatology. It provides an overview of the microorganisms responsible for skin diseases and the challenges posed by drug-resistant strains, emphasizing the need for alternative therapeutic approaches. Subsequently, the review examines a wide array of studies investigating the use of polyherbal gel formulations for treating skin diseases, categorizing them based on their active ingredients and modes of action. This comprehensive assessment reveals not only the potential effectiveness of these formulations but also their comparative advantages over conventional treatments. Mechanisms of action are elucidated, discussing how polyherbal gels exhibit antimicrobial, anti-inflammatory, and wound-healing properties, offering multifaceted support in combating skin diseases. Safety concerns and potential side effects are also addressed to provide a holistic view of the clinical and practical aspects of using polyherbal gels on the skin. This aspect is vital for understanding the risks and benefits associated with these formulations. Furthermore, the review touches upon the challenges of maintaining quality and standardization in polyherbal gel formulations, emphasizing the importance of regulatory guidelines and quality control measures for ensuring product safety and efficacy. The paper highlights the results of clinical trials and case studies, providing insights into the real-world application of polyherbal gels. Promising findings, as well as limitations, are discussed, offering a balanced perspective on the potential of these formulations.
Keywords: Polyherbal gels, skin diseases, microorganisms, antimicrobial properties, clinical trials, phytochemicals
Edition: Volume 12 Issue 12, December 2023,
Pages: 539 - 550