Development of Hydroxy Ethyl Cellulose based (HEC) Gold Nanocomposites Hydrogels for Antimicrobial Application

Alvakonda Narayanamma

Abstract: The presence of gold nanoparticles in the HEC film is confirmed by UV-Vis spectroscopy, Fourier Transform Infrared (FTIR) spectroscopy and X-ray Diffraction (XRD) analysis. The Scanning Electron Microscopic (SEM) images provide the information embedded gold nanoparticles throughout the films. In addition, the formed gold nanoparticles have an average particle size of gold and silver are estimated to be about 5 and 8 nm observed by Transmission Electron Microscopy (TEM). The anti-microbial activity of the gold nanoparticle films has demonstrated significant effects against Escherichia coli (E. coli) and Bacillus. The present study illustrates novel antimicrobial films which are potentially useful in treating infections.

Keywords: HEC film, Gold nanoparticles, anti-microbial