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Case Studies | Anaesthesiology | India | Volume 12 Issue 10, October 2023

A Case of Suspected Anaphylactic Reaction to Propofol Leading to Difficult Intubation

Dr. Sanjay Kumar K A | Dr. Prasad K Kulkarni

Abstract: This article highlights the significance of recognizing and managing perioperative anaphylaxis, with a particular focus on a case involving suspected anaphylactic reaction to propofol during anaesthesia induction. While such occurrences are relatively rare, they can lead to life-threatening situations, underscoring the importance of prompt and effective response strategies. The discussion delves into the immunological mechanisms behind allergic and non-allergic anaphylaxis, shedding light on the role of propofol as a potential allergen. The incidence, diagnostic challenges, and treatment approaches for propofol-induced anaphylaxis are thoroughly explored. This case emphasizes the need for vigilant preoperative assessment, preparedness, and the pursuit of allergologic investigations to pinpoint causative agents and mitigate future occurrences.

Keywords: perioperative anaphylaxis, propofol, allergic reactions, anesthesia induction, immunological mechanisms, treatment strategies

Edition: Volume 12 Issue 10, October 2023,

Pages: 597 - 598