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Research Paper | Medical Science | Volume 11 Issue 9, September 2022 | Pages: 1092 - 1097 | India
Vitamin D Receptor Gene Polymorphism in Type 1 Diabetes Mellitus
Abstract: Background: Polymorphisms within the VDR gene have been associated with altered gene expression or gene function. Vitamin D polymorphism is associated with the development and the severity of several autoimmune diseases such as RA, MS, SLE, IBDs, and T1DM. This study is designed to establish any potential association of VDR polymorphism in patients with type 1 DM. Methods: This study was a hospital based case control study done among 40cases and 40 healthy controls. Type1DM cases were selected based on ADA 2020 guidelines. Vitamin D receptor Polymorphism was assessed using ARMS PCR technique. Vitamin D levels were estimated using ELISA. The statistical analysis was done using SPSS 21.0, p value of
Keywords: Type 1 Diabetes Mellitus, Vitamin D receptor (VDR), Polymorphsim, ARMS PCR
How to Cite?: Dr. Barkha Jain, Dr. Subhalakshmi Das, Dr. Gargi Choudhury, Dr. Neelakshi Bhattacharyya, "Vitamin D Receptor Gene Polymorphism in Type 1 Diabetes Mellitus", Volume 11 Issue 9, September 2022, International Journal of Science and Research (IJSR), Pages: 1092-1097, https://www.ijsr.net/getabstract.php?paperid=SR22924144412, DOI: https://dx.doi.org/10.21275/SR22924144412