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Review Papers | Nanotechnology | India | Volume 11 Issue 9, September 2022
Oral Thin Films: A Novel Immediate Release Dosage Form and Drug Delivery System
Rashmi Patil  | Yash Kothari
Abstract: Oral thin films are the recently emerging novel drug delivery systems which are believed to be enormously expanding their horizons and potentials in the pharmaceutical sector across the world. The dosage form was first developed in 1970?s with the viewpoint of geriatrics, pediatrics and patients experiencing difficulty in swallowing the conventional dosage forms. The OTFs are designed in a manner such that on contact with the wet surface i.e., the tongue, the medication can be consumed owing to its instantaneous dissolution in the oral mucosa without need of water. The advantage of the Oral thin film is the drug enters directly into the systemic circulation bypassing the first pass metabolism. The dosage from can be regarded as highly versatile due to ease of self-administration and high patient compliance. This review is an attempt to comprehensively put together the formulation aspects, manufacturing processes as well as the evaluation parameters of this promising dosage form that can revolutionize the world of medicine and pharmacy.
Keywords: Oral Thin Films, OTFs, Solid Dispersion, Hot-Melt Extrusion
Edition: Volume 11 Issue 9, September 2022,
Pages: 663 - 669