A Case Report on Dengue Fever Complicated with Thrombotic Thrombocytopenic Purpura

Simoni Shah, Tanmay Jain, Dr. Jayesh J. Dutt, Dr. Ibrahim Malek

Abstract: Thrombotic thrombocytopenic purpura (TTP) is a rare disorder with an incidence of 4?5 cases per million per year. It has significant morbidity and mortality if left untreated. Timely diagnosis and availability of effective treatment such as plasma exchange therapy have reduced the morbidity and mortality significantly. Usually, it is idiopathic or Autoimmune, but several predisposing factors have been Described to cause secondary TTP. In this case report, we discussed a very rare presentation of TTP secondary to dengue Virus infection and how the timely diagnosis along with the immediate institution of appropriate management helped us to cure the patient.

Keywords: Dengue Plasmapheresis, Hemodialysis, Renal Failure, Schistocytes