International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


Downloads: 0 | Views: 174

Research Paper | Medical Science | India | Volume 11 Issue 8, August 2022 | Rating: 4.2 / 10


Formulation and Characterization of Macitantan Nanoparticles for the Treatment of Pulmonary Hypertension

A Pandey [61]


Abstract: Nanomedicine is an emerging field with great opportunities to improve the treatment of diseases which are currently not curable. Pulmonary arterial hypertension (PAH) is one of these diseases treatable by inhalation of medicines that provide novel depots for drugs with short pharmacological half - lives to improve the quality of life for patients. In this study, positively charged nanoparticles based on chitosan were developed and synthesized to enhance penetration capability of Macitentan in order to improve the treatment to cure pulmonary arterial hypertension (PAH). This study focuses on the design and characterization of drug delivery systems with the potential to improve the treatment options for hypertonic conditions (like PAH).


Keywords: Pulmonary arterial hypertension, Nanoparticles, preparation, characterization


Edition: Volume 11 Issue 8, August 2022,


Pages: 279 - 281


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