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Research Paper | Pharmacology and Toxicology | India | Volume 11 Issue 7, July 2022

In-Vitro & In-Vivo Evaluation of Anti-Inflammatory and Anti-Oxidant Activity on Hyptis Suoveolens (Seeds) & Tribulus Terrestris (Fruit)

Preethi Garapati

Abstract: Objective: The main objective is to study on anti-inflammatory and anti-oxidant activity on various animal models by using In-vitro and In-vivo anti-inflammatory activity on chloroformic extract of Hyptis Suoveolens seeds and N-hexane extract of Tribulus Terrestris fruit. The study confirmed the calm of the drug use in reducing inflammation. The compounds responsible for reducing inflammation are in progress of identification. Materials and methods: Hyptissuaveolens seeds and Tribulusterrestris fruit were extracted and subjected to protein denaturation using eggalbumin and gelatin zymography studies. The extract was screened for anti-inflammatory activity in albino rats using acute carrageenan induced paw edema in rats, egg albumin induced inflammation and hot-plate test. Results: The extract shows the presence of chemical compounds with chloroform, n-hexane and methanol and in-vivo anti-inflammatory activity was done by the acute models. Conclusion: The extract of hyptissuaveolens seeds and tribulusterrestris fruit showed anti-inflammatory activity in acute and chronic study in albino rats.

Keywords: Hyptissuaveolens seeds, Tribulusterrestris fruit, diclofenac sodium, albino rats

Edition: Volume 11 Issue 7, July 2022,

Pages: 1211 - 1218