Development of Antimicrobial Resistance in Salmonella Typhi and Challenges in Treatment

Bhrigu Singh Parihar

Abstract: Salmonella typhi a human specific pathogen is known to cause a febrile condition known as typhoid or enteric fever. The proper treatment with antimicrobials is needed to save life of person infected as; in severe conditions the infection may lead to meningitis and perforations in the intestines. In the recent years development of resistance in the Salmonella typhi against various antimicrobials has emerged as a matter of concern. Combating these resistance and developing new treatment strategies against multi-drug resistant Salmonella typhi can help in lessening the human burden.

Keywords: Salmonella typhi, multi-drug resistance, drug resistance, treatment strategies, enteric fever