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Comparative Studies | Surgery | India | Volume 11 Issue 12, December 2022

Study of Efficacy of Topical Insulin Application in Wound Healing in Diabetic Foot Ulcers

Sandharbh Gautam | Akhil Kumar Gupta ^[5]

Abstract: Aim: To study the effectiveness of Topical Insulin on healing of Diabetic Ulcer Objective: 1. To find out the advantages of Topical Insulin in management of Diabetic Foot Ulcer.2. To assess the wound healing of diabetic foot ulcer after applying topical insulin. Material and Methods: This is a Hospital - based prospective observational study involving 100 patients presenting with diabetic foot ulcers in Department of General Surgery in Muzaffarnagar Medical College during a period of 1 year from January 2021 to January 2022. Results: In our study, there was no significant difference in mean age between case (50.14?8.22 years) and control groups (49.44?8.46 years). Majority of the study population belonged to 46 - 55 years (60.0%) followed by 35 - 45 years (14.0%) and above 55 years (26.0%). The mean Wound size Post - treatment and Change from pre to post treatment was significantly more among Topical Insulin group compared to control group. The mean Percent reduction in size of ulcer was significantly more among Topical Insulin group compared to control group. In present study, the mean Hospital stay (in days) was significantly more among control group compared to Topical Insulin group. Conclusion: Insulin has a favorable impact on wound healing and is widely acknowledged as a critical factor in wound healing.

Keywords: Topical Insulin, Diabetic Foot, IGF

Edition: Volume 11 Issue 12, December 2022,

Pages: 511 - 513