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Research Paper | Pharmacology Science | India | Volume 11 Issue 11, November 2022

Total Phenolic, Total Flavonoid and Free Radical Scavenging Potential of Moringa Oleifera Leaf and Tribulus Terrestris Fruit Extracts

Rakesh H | P Mahaboob Basha

Abstract: This study investigated the antioxidant potential and free radical scavenging ability of ethanolic extracts from Tribulus terrestris fruit (TTF) and Moringa oleifera leaf (MOL) ethanolic extract. The antioxidant and free radical scavenging activities were measured by using standard protocols for the doses using 50, 100, 150, 200 and 250 ?g/ml concentrations. Total phenolic and flavonoid content were estimated using the Folin-Ciocalteu method. Among the extracts, MOL showed the highest total antioxidant ability followed by TTF. With regard to various scavenging activities, MOL had the highest radical scavenging activity than TTF extract closely resembled the standards. Also, the reducing capacity on ferrous ions was high in MOL than TTF. The phenolic contents of TTF and MOL ethanolic extracts were quantified. A positive correlation (p value<0.001) was observed between phenolic content and free radical scavenging efficiencies. The results confirm that both MOL and TTF are important sources of natural antioxidants and serves as an effective free radical scavenger and/ or inhibitors. Hence, both extracts are suitable plant-based products that can be used as pharmaceutical agents to handle 'free radical-mediated diseases.

Keywords: Antioxidant potential, free radical scavenging ability, Moringa oleiferaleaf extract, Tribulus terrestrisfruit extract, pharmaceuticals

Edition: Volume 11 Issue 11, November 2022,

Pages: 1363 - 1373