Tailaring, Characterization, & Microbiological Evaluation of Heterocyclic Moiety

Aarohi Ahuja, Ujjwal Prakash Jajodia, Abhishek Shandilya, Anil Kumar Koshal

Abstract: The presents work deals with tailoring of heterocyclic compounds which bearing hetero atoms such nitrogen, sulphur and oxygen. Heterocyclic moiety is an important class for pharmaceutical applications. All synthesized compounds are identified by spectral data. Reaction progress and competition of reaction monitored by the TLC. The structures of the synthesised compounds were analysed by spectral data from IR (Fourier-transform infrared spectroscopy) and 1H-NMR, which revealed the expected frequencies and signals. The investigated compounds were screening for microbiological activities against Gram-positive bacteria, Gram-negative bacterial strains in which some compounds showed excellent activity while some exhibited moderate activity against bacterial stains.

Keywords: Heterocyclic, IR, H-NMR, Microbial activity