International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064

Downloads: 1 | Views: 31

Case Studies | Medical Science | India | Volume 11 Issue 1, January 2022

EVANS Syndrome - A Rare Cause of AIHA with ITP: A Case Report

Dr Shruti Bharat Nelekar | Dr M. A. Jamadar

Abstract: Background: Evan's syndrome is a rare autoimmune hematological condition, characterized by warm antibody AIHA with ITP with or without neutropenia. Secondary associations may include connective tissue disorders, infections and malignancies. Introduction: We present a case of a middle aged female patient who presented with anemia, bleeding manifestations refractory to repeated transfusions. Clinical features and laboratory and immunological workup was done and diagnosis was Evan's syndrome was made. Interventions: blood transfusion initially given to alleviate symptoms and corticosteroids were started. Outcome: with corticosteroids patient experienced dramatic improvement and patient is being followed up monthly and no remission is observed with the steroid doses being tapered. Conclusion: It can be concluded that considering Evan's syndrome in the differential diagnosis of AIHA and ITP can help to initiate early treatment with steroids, IVIG or immunemodulators and prevent the dreadful complications of massive bleeding.

Keywords: AIHA, ITP, neutropenia, autoimmune disorder, corticosteroids, IVIG, Immunomodulators

Edition: Volume 11 Issue 1, January 2022,

Pages: 184 - 187

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