Estimation of Glomerular Filtration Rate by using Two Different Methods for Creatinine Estimation in Chronic Kidney Disease: Comparative Study

Shipra Shrivastava

Abstract: CKD is rapidly raising epidemic with increasing prevalence in India due to raised diabetes and hypertension cases. This study was proven cases of CKD (n = 100) admitted in the hospital between January 2019to December 2019 at Rajeev Gandhi College and General Hospital, Bhopal were included in the study. Serum creatinine was measured by Jaffe?s and creatininase-creatininase methods and gfr was calculated using conventional formula and Cockcroft-gault formula. 100 patients were selected with male predominance and average mean age group is the CKD cases. Determined that the CGF formula produces better results, than the creatinine clearance obtained with conventional in patients, stating that creatinine clearance obtained by using enzymatic creatinine method with COCKCROFT ?GAULT formula correlates better.

Keywords: Creatinine, CKD, GFR, Diabetes, enzymatic reactions