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Research Paper | Ophthalmology | India | Volume 10 Issue 11, November 2021
Comparison of Retinal Nerve Fibre Layer Thickness in Diabetic Patients with and without Diabetic Retinopathy Using OCT (Optical Coherence Tomography)
Anil Kumar Bhupally [3] | Raghu V [3] | Sindu Sulekha Chigiri [2] | Sidhartha A
Abstract: Purpose: This study intent to highlight the OCT characteristics of the RNFL in patients with diabetic retinopathy. To evaluate the association if any of RNFL thickness with diabetic retinopathy and to evaluate possibility of RNFL thickness changes as precursor to diabetic retinal changes. Methods and Methodology: This study was conducted at Department of Ophthalmology Chalmeda Ananda Rao Institute of Medical Sciences from Aug - 2019 to Jan - 2020.100 patients fulfilling inclusion and exclusion criteria were included in the study. All patients were subjected to detailed systemic and ophthalmic evaluation and Investigations like Blood Sugars Sr. Creatinine Sr. Cholesterol were done. Inclusion Criteria: Patients with diabetes mellitus over 40 years of age. Exclusion Criteria: Recent ocular surgery (1month) pseudo exfoliation pigment dispersion syndrome thyroid dysfunction long term steroid user?s high myopia media opacities other causes for secondary glaucoma post glaucoma surgery. Results: The Average RNFL thickness in the study was 93.92 micrometres. Average inferior superior nasal RNFL thickness? is not significant across groups. The average temporal RNFL thickness in the study was 65.02 micrometres and it was significantly thicker (p0.01) across groups. Conclusion: An early increase intemporal RNFL thickness in some stages of diabetic retinopathy could be indicator of impending CSME.
Keywords: Diabetic Retinopathy, Optical Coherent Tomography, Retinal Nerve Fibre Layer Thickness, Apoptosis, Type 2 Diabetes
Edition: Volume 10 Issue 11, November 2021,
Pages: 1149 - 1154