Ocular Surface Squamous Neoplasia - A Clinical Study

L. Rajitha, P. Vishwamitra

Abstract: Aim: To analyse the demographic distribution and the various clinical presentation, treatment outcomes and histopathological features of OSSN. Methods: Study conducted at tertiary eye care centre from DEC 2014 TO JUNE 2016 on 25 patients with clinical features suggestive of OSSN. All patients underwent excision biopsy with cryotherapy. Results: 25 cases were proven as OSSN on HPE. Most common age group 30 -50 years. Left eye was involved in 52%of patients. Nasal quadrant was involved most commonly. Clinically gelatinous pattern seen in 48% of cases. On HPE dysplasias seen in 72% of cases. Excisional biopsy with cryotherapy was done. Complications include 1 case of SPK with conjunctival granuloma & a case of corneal thinning with iris prolapse and scleral thinning. Mean follow up period was 17 months. No recurrence was seen. Conclusions: OSSN most commonly found in males and outdoor workers. Most common presentation is mass followed by foreign body sensation. On HPE dysplasias seen in 72% of cases. Excisional biopsy with cryotherapy is associated with best control of primary OSSN with no tumour recurrence.

Keywords: OSSN, Squamous cell carcinoma, Carcinoma in situ, Dysplasia