International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


Downloads: 5 | Views: 52

Research Paper | Chemistry | India | Volume 10 Issue 4, April 2021 | Rating: 4.6 / 10


An Efficient Synthesis for Novel 2, 3-Disubstituted -4-Thiazolidones and Antimicrobial Evaluation

Kishor Huge | Vasant Gurav


Abstract: Novel 2-Methyl (2?-hydroxy-3?/5?-chloro-5?/3?-chloromethyl phenyl)- 3- ( 3?/4?-sustitutedphenyl)-4-thiazolidones are synthesized from 2-Hydroxy-3/5-chloro-5/3-chloromethyl acetophenone in good yield with purity. The structure of these compounds are confirmed by IR, 1H NMR and Mass spectra of a representative member from the series. These novel derivatives are then screened for antibacterial and antifungal activities against S. aureus, E. coli, X. citri, E. carotovora, C. albicans, T. rubrum, A. solani and H. turcicum.


Keywords: 2-Hydroxy-3/5-chloro-5/3-chloromethyl acetophenone, 2, 3-Disubstituted-4-thiazolidones, Antibacterial, Antifungal


Edition: Volume 10 Issue 4, April 2021,


Pages: 905 - 908


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