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Research Paper | Chemistry | Volume 10 Issue 4, April 2021 | Pages: 905 - 908 | India
An Efficient Synthesis for Novel 2, 3-Disubstituted -4-Thiazolidones and Antimicrobial Evaluation
Abstract: Novel 2-Methyl (2?-hydroxy-3?/5?-chloro-5?/3?-chloromethyl phenyl)- 3- ( 3?/4?-sustitutedphenyl)-4-thiazolidones are synthesized from 2-Hydroxy-3/5-chloro-5/3-chloromethyl acetophenone in good yield with purity. The structure of these compounds are confirmed by IR, 1H NMR and Mass spectra of a representative member from the series. These novel derivatives are then screened for antibacterial and antifungal activities against S. aureus, E. coli, X. citri, E. carotovora, C. albicans, T. rubrum, A. solani and H. turcicum.
Keywords: 2-Hydroxy-3/5-chloro-5/3-chloromethyl acetophenone, 2, 3-Disubstituted-4-thiazolidones, Antibacterial, Antifungal
How to Cite?: Kishor Huge, Vasant Gurav, "An Efficient Synthesis for Novel 2, 3-Disubstituted -4-Thiazolidones and Antimicrobial Evaluation", Volume 10 Issue 4, April 2021, International Journal of Science and Research (IJSR), Pages: 905-908, https://www.ijsr.net/getabstract.php?paperid=SR21420151048, DOI: https://dx.doi.org/10.21275/SR21420151048