Effects of Synergist Piperonyl Butoxide (PBO) on Deltamethrin Tolerance in Anopheles Gambiae sensu lato Larvae from Mono Department in South-Western Benin, West Africa

Nazaire Aizoun

Abstract: The current study was aimed to study the effects of synergist piperonyl butoxide (PBO) on deltamethrin tolerance in Anopheles gambiae sensu lato larvae from mono department in south-western Benin, West Africa. Larvae and pupae were collected from March to July and August to November 2018 during the rainy season in the locations of Athieme, Grand Popo, Come, Lokossa, Houeyogbe and Bopa. Larval bioassays were performed on these collected Anopheles gambiae sensu lato larvae using deltamethrin as larvicide and piperonyl butoxide (PBO) as enzyme inhibitor or synergist. The results showed that mono-oxygenases played a role in Anopheles gambiae sensu lato larvae tolerance to deltamethrin.

Keywords: deltamethrin, piperonyl butoxide, tolerance, malaria vectors, Benin