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Research Paper | Biotechnology | India | Volume 9 Issue 8, August 2020
Pain, Reveling the Knotted Threads about Causes and Management
Abstract: It is said that we live within the world of pain and sufferings, be it spiritual, mental or physical, the pain is usually hurting and results in discomfort. In context to biology, once we get a cut or a burn, what can we feel at that moment or after a while [in some cases] is that the experience of a sensation, called pain. Pain might be considered, in physiology, as any sensation which is unpleasant and may make us uncomfortable in both physical and mental context. The experience of pain or feeling of pain are often thanks to injuries or trauma, so, we will say that injury or trauma is that the phenomenon which provides us the feeling of pain. Is pain only a fitness or is it a state of mind? once we get a cut at fingertip while cutting vegetables or doing stationary work, we quickly desire leaving the work and sit somewhere to sooth down the cut area, but how can we experience pain; that's the pain which don't allow us to continued within the former work. But why can we experience the pain of such a little cut while we don't experience any kind of pain during operation operational theatre. rather than the physical changes that lead us to experience pain like inflammation or could also be the other mechanism of which we are still unknown, this is often the signal that gets to the brain from the affected area that, where we had cut and that we do experience pain. If we got a cut or burn, we do get pain which lets us to get rid of our hand from the place that hurts us and is liable for pain, so can we conclude that pain may be a defensive mechanism or is it something else? The pain is experienced when any quite tissue damage occurs which it's sensed by the neuronal network which is bedded everywhere in our body that connects every a part of body to brain and from there the signal is received and eventually we revisit another signal for response to the stimuli. Stimuli are any quite external changes that cause some kind of signal transduction in our body. Pain are often experienced only we sense in by our senses and when signal from brain comes in response thereto. this is often no way different from any of the reflex action that would cause response against stimuli, so pain also can be a mechanism which is protective so as to urge rid from things that cause pain. Pain can be due to several reasons or some time could be without any specific reason too; it could be due to cut, burn, surgery, internal trauma, disease or it could be due to stress which leads to secretion of several kinds of neurotransmitter which make us feel pain. As we know science is changing day by day it is growing its arm to a great level but science should not be restricted to a person who is an academician, scientist or a researcher, it should be well know by all. Who [anyone whether science associated or not] wanted to know about should be informed as much as possible, in this research paper by taking several references and used easy language for better understanding of everyone who would read it, I had tried my best to make it explained all about pain and the some of the mechanism of pain management, here I have also explained the mechanism of action of pain killers, that can affect us badly.
Keywords: Pain management, neurotransmitters, synapsis, pain receptors
Edition: Volume 9 Issue 8, August 2020,
Pages: 317 - 325