Study of the Effect of pH on the Cleaning of Fexofenadine in a Stainless-Steel Reactor by the Rinsing and Swabbing Method

Fateh Naitali, Hafida Ghoualem

Abstract: The cleaning in the pharmaceutical industry is involved in each process of manufacture of drugs, it assure the quality of the final product. Cleaning is a key position in the fight against the risks of cross-contamination (chemical, microbiological and particulate) of drugs. The aim of this work is the study of the influence of pH on the cleaning of fexofenadine in a stainless steel reactor. Two cleaning methods were studied, the rinsing method and the swabbing method.

Keywords: Pharmaceutical industry, fexofenadine, cleaning rinsing, swabbing, pH