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Informative Article | Medicine | India | Volume 9 Issue 6, June 2020
Use of Mefenamic Acid as a Supportive Treatment of COVID-19: A Repurposing Drug
Abstract: COVID-19 (coronavirus disease 2019) is a Pandemic of concern, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). As of now, there is no known effective pharmaceutical or other medicine available for cure or prevention of COVID-19. In this review, based on the current understanding of the disease and the structure of novel Coronavirus SARS-CoV-2, SARS-CoV and other human viruses, I have identified Mefenamic Acid, an anti-inflammatory medicine, of having some role as an anti-viral medicine also. It can be used along with different anti-viral drugs being tried for the treatment of Covid 19. Since it is also an anti-pyretic, its main role may be of bringing down the fever but its action as an anti-viral, as a supportive medicine can very useful. Clincal trials with this concept in mind can be started immediately at the Centre dedicated for treatment of Covid 19.
Keywords: COVID-19, SARS-CoV-2, Mefenamic acid, serine protease inhibitor, NLRP3 inflammasome
Edition: Volume 9 Issue 6, June 2020,
Pages: 69 - 73