Attenuation of Haemodynamic Responses to Laryngoscopy and Endotracheal Intubation using Esmolol and Lignocaine - A Comparative Study
Abstract: AIM: To compare the efficacy of Esmolol Hcl & Lignocaine Hcl in attenuation of hemodynamic response to Laryngoscopy and Endotracheal Intubation. MATERIALS & METHODOLOGY: A randomized, prospective, double-blind study in which 60 patients of ASA grade I or II aged between 20–60 years was conducted. LignocaineHcl 1 mg/kg and Esmolol Hcl 0.5 mg/kg were compared in attenuating the haemodynamic response to laryngoscopy and tracheal intubation in elective surgery under general anaesthesia. Patients were divided into two groups Group L (Lignocaine): patients receive injection Lignocaine, 1 mg/kg IV bolus diluted to 10 ml with 0.9 % saline. Group E (Esmolol): patients receives injection Esmolol 0.5 mg/kg IV bolus diluted to 10 ml with 0.9 % saline. All the selected patients are subjected to the same anaesthesia technique. HR, SBP, DBP and MAP were recorded before intubation, and then during intubation 0 minute, 1 min, 3 min, 5 min of intubation. RESULTS: Systolic, Diastolic & Mean Arterial Pressures increased significantly in lignocaine group whereas it was attenuated more effectively in Esmolol group (p
Keywords: Esmolol, Lignocaine, haemodynamic response, General anaesthesia
How to Cite?: Dr. M. Venkat Rama Rao, Dr. T. Surya Sree, "Attenuation of Haemodynamic Responses to Laryngoscopy and Endotracheal Intubation using Esmolol and Lignocaine - A Comparative Study", Volume 9 Issue 3, March 2020, International Journal of Science and Research (IJSR), Pages: 1086-1088, https://www.ijsr.net/getabstract.php?paperid=SR20317161100, DOI: https://dx.doi.org/10.21275/SR20317161100