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Research Paper | Pathology | India | Volume 6 Issue 7, July 2017
Correlation of Elevated Mast Cell Density with Microvessel Density in Various Grades of Oral Submucous Fibrosis
Dr Sabu Paul [4] | Dr Pramod P Mathews [3]
Abstract: Aim: To correlate the elevated mast cell density with the microvessel density in various grades of oral submucous fibrosis. Materials and Methods: H and E stained sections of oral submucous fibrosis (OSMF) were examined and microvessel density (MVD) quantified using an image analyzer. Mast cell density (MCD) calculated using a microscope fitted with a calibrated mechanical stage. Statistics: ANOVA was used to test the equality of means between MVD and MCD. Results: Mast cell density showed a consistent increase with Microvessel density in different grades of OSMF although the correlation was statistically insignificant. Discussion: Mast cells play a significant role in inducing angiogenesis in OSMF and modalities to control mast cell mediators would in turn improve the prognosis of OSMF patients.
Keywords: mast cell density, microvessel density, image analysis, oral submucous fibrosis
Edition: Volume 6 Issue 7, July 2017,
Pages: 2275 - 2277
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Research Paper, Pathology, India, Volume 6 Issue 6, June 2017
Pages: 2845 - 2847Association of Degranulated Mast Cell Count with Burning Sensation of Oral Cavity in Oral Submucous Fibrosis
Dr Sabu Paul [4] | Dr Pramod P Mathews [3]
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Case Studies, Pathology, India, Volume 10 Issue 8, August 2021
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