Zincoxide Nanocomposite Hydrogels of Poly (N-tert-amylacrylamide ?co ?N-VinylPyrrolidone) Poly (N-tert-butylacrylamide ?co ?N-VinylPyrrolidone) Poly (N-cyclohexylacrylamide ?co ?N-VinylPyrrolidone)-Synthesis and Characterisation

R. Krithika, P. Jeyanthi, P. Pazhanisamy

Abstract: In this study, we synthesised a chains of Poly (N-tert-amylacrylamide co N-VinylPyrrolidone) ZincOxide nanocomposite hydrogel (Poly (NTA-NVP) ZnO), Poly (N-tert-butylacrylamide co N-VinylPyrrolidone) ZincOxide nanocomposite hydrogel (Poly (NTB-NVP) ZnO), Poly (N-cyclohexylacrylamide co N-VinylPyrrolidone) ZincOxide nanocomposite hydrogel (Poly (NCA-NVP) ZnO), by a free-radical polymerization using Azo- bis- iso -butyronitrile (AIBN) and N, N-methylene-bis-acrylamide (MBA) initiator and cross-linking reagent respectively. These ZincOxide Nanocomposite hydrogels were characterized by Fourier transfom infrared Spectroscopy, X-ray diffraction and SEM analysis. Drug, Protein loading and the release behaviour were studied using UV Visible spectroscopy. The swelling nature of the hydrogel were studied by gravimetric method.

Keywords: copolymerization, hydrogel, swelling, free radical polymerization