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Case Studies | Biochemistry Science | India | Volume 3 Issue 11, November 2014

Study of Serum Insulin and Insulin Resistance in Hypothyroid Patients in Jodhpur Region (Rajasthan)

Gupta Ritu ^[3] | Dr. Mathur Ranjana | Kumar Rohitash

Abstract: Background: Disorders affecting the thyroid gland are the most common endocrinopathies. Hypothyroidism can lead to symptoms that reduces the functional status and quality of life.17 patients of clinically established patients of hypothyroidism attending Out Patient Departments, MDM hospital Jodhpur (Rajasthan) were compared with 25 healthy subjects of either sex in Department of Biochemistry, Dr S. N. Medical College, Jodhpur for thyroid function tests and serum insulin. Method: Serum T3, Serum T4, Serum TSH and Serum Insulin were measured by ELISA technique while Fasting Insulin Resistance Index (FIRI) was calculated by HOMA-IR formula. Results: Serum T3, Serum T4 and Serum TSH of hypothyroid patients showed a highly significant (p0.05) relationship. Conclusion: Estimation of serum insulin is simple, reliable, economic and sensitive and it can be used in the proper management of chronic complications of thyroid disorders.

Keywords: FIRI, Insulin, Hypothyroidism, Insulin-resistance, TSH

Edition: Volume 3 Issue 11, November 2014,

Pages: 745 - 746