International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064

Downloads: 107 | Views: 152

Research Paper | Microbiology | India | Volume 3 Issue 10, October 2014

Metallo-β- Lactamase Producing Clinical Isolates in a Tertiary Care Hospital

S. Basireddy | Singh M [24] | Reddy H [3] | Ali S [189] | Kabra V

Abstract: Metallo-- lactamase (MBL) producing carbapenem resistant clinical isolates are an increasingly difficult problem in health care settings because of the treatment difficulties and rapid spread of these infections. The present study aims in detecting the MBL production among carbapenem resistant clinical isolates.54 non repetitive clinical isolates of carbapenem resistant gram negative bacteria were studied to detect the Metallo-- lactamase production. Among them 20 (37 %) were MBL producers. MBL producers are predominantly observed among Enterobacteriaceae members with E. coli topping the list (81.8 %) followed by Klebsiella (77.8 %). The least number of MBL producers were observed among Acinetobacter isolates (9.6 %). Timely detection of these infections along with the stringent infection control practices will prevent the spread of these bacteria in health care settings.

Keywords: Metallo-- lactamase, E strips, carbapenem resistance, enterobacteriaceae, acinetobacter

Edition: Volume 3 Issue 10, October 2014,

Pages: 1324 - 1326

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