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Research Paper | Biology | Bosnia and Herzegovina | Volume 5 Issue 1, January 2016

Influence of Basic Variables on Micronucleii Frequency in General Population of FB & H

Mirela Mackic-Durovic ^[2] | Izeta Aganovic-Musinovic | Orhan Lepara | Slavka Ibrulj ^[2]

Abstract: The aim of this study was to determine the value of micronuclei test (MN) on peripheral blood lymphocytes from 200 healthy participants of both gender from general population of FB & H, as well as to determine if the gender, age or smoking habit have influence on MN frequency. Standard protocol for MN test cultivating and micronuclei analyzing from peripheral blood binuclear lymphocytes have been applied. Results have presented that range of singe values are from 0 to 8 MN in 1000 binuclear cells. It has been determined that gender, age and smoking habit do have influence on MN frequency, especially on 2 MN frequencies. Females on average do have higher values of all variables of MN test than men. It has been proven that smoking habit do have influence on increased number of cells with 2MN, as well. The results of this study will help to form data base as start for comparative research in future.

Keywords: micronuclei, age, gender, smoking habit

Edition: Volume 5 Issue 1, January 2016,

Pages: 159 - 162