A Case of Non Ketotic Hyperglycemic-Hemichorea Hemiballismus Syndrome
Abstract: Diabetic striatopathy is a rare cause of involuntary movements associated with poorly controlled diabetes. A 50-year-old woman with longstanding type 2 diabetes presented with spontaneous, painful movements that began in the right hand and progressed to the entire right upper limb over three days. Her blood glucose was 401 mg/dL, and glycated hemoglobin was 16.3%, reflecting poor glycemic control. Brain imaging revealed abnormalities in the left putamen and globus pallidus, opposite the affected limb. The clinical presentation and imaging findings were considered consistent with nonketotic hyperglycemic hemichorea-hemiballismus syndrome. Treatment included insulin adjustment and risperidone for movement control. The frequency and intensity of involuntary movements decreased before discharge on the fourth hospital day. At one-month follow-up, symptoms persisted but continued to improve. This case highlights the importance of considering diabetic striatopathy in patients with poorly controlled diabetes who develop acute involuntary movements on one side of the body. Early recognition and appropriate treatment may support motor recovery.
Keywords: Diabetic striatopathy, Nonketotic hyperglycemia, Hemichorea-hemiballismus, Type 2 diabetes, Involuntary movements
How to Cite?: Dr. Kondaparthi Harish, "A Case of Non Ketotic Hyperglycemic-Hemichorea Hemiballismus Syndrome", Volume 15 Issue 10, October 2026, International Journal of Science and Research (IJSR), Pages: 71-72, https://www.ijsr.net/getabstract.php?paperid=MR26929141602, DOI: https://dx.doi.org/10.21275/MR26929141602