Efficacy of Intravenous Dexamethasone in Patient with Postpartum Hellp Syndrome-Randomised Controlled Double Blinded Study
Abstract: Background: HELLP syndrome is a severe obstetric complication characterized by hemolysis, elevated liver enzymes, and low platelet count, associated with significant maternal morbidity and mortality. The role of postpartum corticosteroids in improving maternal recovery remains controversial. Objectives: To evaluate the effect of postpartum dexamethasone on clinical and biochemical recovery in women with HELLP syndrome. Materials and Methods: This prospective randomized double-blind controlled study was conducted in the Department of Obstetrics and Gynaecology at Ballari Medical College and Research Centre. A total of 30 postpartum women diagnosed with HELLP syndrome were randomly allocated into two groups: dexamethasone group (n=15) and control group (n=15). The study group received intravenous dexamethasone (30 mg over 36 hours), while the control group received standard care. Clinical parameters and laboratory indices were monitored serially. Statistical analysis was performed using SPSS, with p
Keywords: HELLP syndrome, dexamethasone, corticosteroids, platelet recovery, liver enzymes, postpartum, maternal outcome
How to Cite?: Dr. Srishti Mannur, Dr Chandrashekhar T, Dr. Pallavi, "Efficacy of Intravenous Dexamethasone in Patient with Postpartum Hellp Syndrome-Randomised Controlled Double Blinded Study", Volume 15 Issue 4, April 2026, International Journal of Science and Research (IJSR), Pages: 635-641, https://www.ijsr.net/getabstract.php?paperid=MR26408184401, DOI: https://dx.doi.org/10.21275/MR26408184401