Aggressive Angiomyxoma of the Vulva in a Postmenopausal Woman Presenting as a Necrotic Pedunculated Mass: A Rare Case Report

Dr Harshitha M, Dr Aparna Nair, Dr Srujana CP

Abstract: Aggressive angiomyxoma is a rare, slow-growing mesenchymal tumor predominantly affecting the pelvis and perineum of women in the reproductive age group. It is characterized by a high propensity for local recurrence despite its benign histology. We report a case of a 49-year-old postmenopausal woman who presented with a painless mass over the right labia majora for two months, associated with foul-smelling discharge. She had attained menopause two years prior and had a history of type 2 diabetes mellitus without regular treatment. Clinical examination revealed a large pedunculated mass measuring 10 ? 5 cm with areas of necrosis and discharge. Right inguinal lymph nodes were palpable. Per speculum examination showed a hypertrophied cervix and vagina. Surgical excision of the mass was performed, and histopathological examination confirmed the diagnosis of aggressive angiomyxoma. This case is notable due to its occurrence in a postmenopausal woman and its atypical presentation with necrosis and foul-smelling discharge, mimicking malignancy. Early diagnosis and complete surgical excision are crucial to reduce recurrence and ensure favorable outcomes.

Keywords: Aggressive angiomyxoma, vulvar mass, postmenopausal, mesenchymal tumor, vulval tumor, recurrence

How to Cite?: Dr Harshitha M, Dr Aparna Nair, Dr Srujana CP, "Aggressive Angiomyxoma of the Vulva in a Postmenopausal Woman Presenting as a Necrotic Pedunculated Mass: A Rare Case Report", Volume 15 Issue 3, March 2026, International Journal of Science and Research (IJSR), Pages: 1417-1418, https://www.ijsr.net/getabstract.php?paperid=MR26323231244, DOI: https://dx.doi.org/10.21275/MR26323231244

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